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. 2010 Jul;31(3):382-6.
doi: 10.4103/0974-8520.77155.

Impact of Bhavana Samskara on physico-chemical parameters with special reference to Gandhaka Rasayana prepared by different media and methods

Shuchi Mitra  1 , P K Prajapati, V J Shukla, B Ravishankar
Affiliations

Impact of Bhavana Samskara on physico-chemical parameters with special reference to Gandhaka Rasayana prepared by different media and methods

Shuchi Mitra et al. Ayu. 2010 Jul.

Abstract

Gandhaka Rasayana is frequently used in the management of different skin disorders (Kushtha). It is a herbo-mineral preparation prepared by Shuddha Gandhaka Bhavit with 11 herbal drugs in a serial manner for eight times each. Therefore, it was used as a model drug and four samples were prepared by adopting different methods and media. The physicochemical parameters were evaluated. The effect of increasing the number of Bhavana (lavigation) on particle size of the drug was examined. Similarly, an attempt was also made to differntiate the structure (surface anatomy) of the drug with Bhavana and without Bhavana by using a very sophisticated x-ray photo electron spectrometer (XPS) study. Overall, a remarkable difference was observed in the samples with Bhavana and without Bhavana.

Keywords: Bhavana; Gandhaka Rasayana; ICP; XPS; particle size.

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Figures

Figure 1
Figure 1
Particle size distribution of all the three samples 10, 50, 90 indicate the percentage of particles e.g. 10% particles are below 0.54 μm in G.R.A sample
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