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. 2011 Dec;121(12):4580-3.
doi: 10.1172/JCI61592. Epub 2011 Dec 1.

Preventing sexually transmitted infections: back to basics

Anne Rompalo  1
Affiliations

Preventing sexually transmitted infections: back to basics

Anne Rompalo. J Clin Invest. 2011 Dec.

Abstract

Sexually transmitted infections (STIs) have plagued humans for millennia and can result in chronic disease, pregnancy complications, infertility, and even death. Recent technological advances have led to a better understanding of the causative agents for these infections as well as aspects of their pathogenesis that might represent novel therapeutic targets. The articles in this Review Series provide excellent updates on the recent advances in understanding of the pathogenesis of some very important and persistent STIs and discuss the importance of considering each pathogen in the broader context of the environment of the individual who it infects.

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Figures

Figure 1
Figure 1. Global estimates of prevalent cases of STIs in 2005.
At any point in 2005, there were approximately 318 million prevalent cases of curable STIs (syphilis, gonorrhea, chlamydia, and trichomonas) and 536 million estimated HSV-2 infections (based on data from ref. 35).
Figure 2
Figure 2. HPV, prevalence studies among female populations, 1995–2001 (reproduced with permission from ref. 36).
See this image and copyright information in PMC

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References

    1. World Health Organization. The Global Elimination Of Congenital Syphilis: Rationale And Strategy For Action. Geneva, Switzerland: WHO Press; 2007.
    1. Tapsall JW. Neisseria gonorrhoeae and emerging resistance to extended spectrum cephalosporins. Curr Opin Infect Dis. 2009;22(1):87–91. doi: 10.1097/QCO.0b013e328320a836. - DOI - PubMed
    1. Centers for Disease Control and Prevention. Sexually Transmitted Diseases Treatment Surveillance 2009. Atlanta, Georgia, USA: US Department of Health and Human Services; 2010.
    1. Ho EL, Lukehart SA. Syphilis: using modern approaches to understand an old disease. J Clin Invest. 2011;121(12):4584–4592. - PMC - PubMed
    1. Fraser CM, et al. Complete genome sequence of Treponema pallidum, the syphilis spirochete. . Science. 1998;281(5375):375–388. doi: 10.1126/science.281.5375.375. - DOI - PubMed

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