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Review
. 2012 Feb;26(1):8-15.
doi: 10.1007/s00482-011-1117-1.

[Clinical application of pain-related evoked potentials]

[Article in German]
N Hansen  1 , M Obermann, N Uçeyler, D Zeller, D Mueller, M S Yoon, K Reiners, C Sommer, Z Katsarava
Affiliations
Review

[Clinical application of pain-related evoked potentials]

[Article in German]
N Hansen et al. Schmerz. 2012 Feb.

Abstract

Pain-related evoked potentials (PREPs) represent a novel method for the evaluation of peripheral and central nociceptive pathways, e.g. in the diagnosis of small fiber neuropathy (SFN) or after therapeutic interventions for headache. Compared to contact heat-evoked and laser-evoked potentials, recording of PREPs is less stressful for the subjects and technically less demanding. The clinical usefulness of PREPs has been described for SFN associated with diabetes, HIV and hepatitis C infections as well as in headache and facial pain disorders. They have also been evaluated after interventional methods, such as direct current stimulation (tDCS). The article reviews and discusses the advantages and pitfalls of this technique in the context of recent clinical studies as compared to other paradigms of peripheral electrical stimulation and delineates perspectives and possible indications.

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References

    1. Eur J Neurol. 2010 Aug;17(8):1010-8 - PubMed
    1. Eur J Pain. 2003;7(3):225-33 - PubMed
    1. Hum Neurobiol. 1984;3(1):33-40 - PubMed
    1. EEG EMG Z Elektroenzephalogr Elektromyogr Verwandte Geb. 1981 Dec;12(4):195-7 - PubMed
    1. J Physiol. 2006 Nov 15;577(Pt 1):235-48 - PubMed

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