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. 2012 Feb;16(1):151-6.
doi: 10.1007/s11030-011-9342-1. Epub 2011 Dec 2.

Spiro[pyrrolidine-2,3'-oxindole] derivatives synthesized by novel regionselective 1,3-dipolar cycloadditions

Gang Chen  1 , Jing Yang, Suo Gao, Hongping He, Shunlin Li, Yingtong Di, Ying Chang, Yang Lu, Xiaojiang Hao
Affiliations

Spiro[pyrrolidine-2,3'-oxindole] derivatives synthesized by novel regionselective 1,3-dipolar cycloadditions

Gang Chen et al. Mol Divers. 2012 Feb.

Abstract

A series of spiro-oxindole derivatives was synthesized by novel regioselective 1,3-dipolar cycloadditions of isatin, α-amino acids, and (E)-β-aryl-nitro-olefins. Regioisomers were produced in each reaction and the major products showed different regioselectivity compared to previously reported spiro-oxindole derivatives.

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References

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