Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation
Review
. 2011 Dec 1;3(12):a011510.
doi: 10.1101/cshperspect.a011510.

Immunoreceptor signaling

Affiliations
Review

Immunoreceptor signaling

Lawrence E Samelson. Cold Spring Harb Perspect Biol. .

Abstract

Antigens bind to immunoreceptors on the surface of T-cells and B-cells, activating signal transduction pathways that allow them to proliferate, differentiate, and synthesize effector molecules involved in the immune response.

PubMed Disclaimer

Figures

Figure 1.
Figure 1.
Early events in T cell and B cell receptor signaling.
Figure 2.
Figure 2.
T cell receptor signaling.

Similar articles

Cited by

References

    1. Andreotti AH, Schwartzberg PL, Joseph RE, Berg LJ 2010. T-cell signaling regulated by the Tec family kinase, Itk. Cold Spring Harb Perspect Biol 2: a002287. - PMC - PubMed
    1. Balagopalan L, Coussens NP, Sherman E, Samelson LE, Sommers CL 2010. The LAT story: A tale of cooperativity, coordination, and choreography. Cold Spring Harb Perspect Biol 2: a005512. - PMC - PubMed
    1. Bradshaw JM 2010. The Src, Syk, and Tec family kinases: Distinct types of molecular switches. Cell Signal 22: 1175–1184 - PubMed
    1. Finlay D, Cantrell D 2010. The coordination of T-cell function by serine/threonine kinases. Cold Spring Harb Perspect Biol 3: a002261. - PMC - PubMed
    1. Huang YH, Sauer K 2010. Lipid signaling in T-cell development and function. Cold Spring Harb Perspect Biol 2: a002428. - PMC - PubMed

MeSH terms

Substances

LinkOut - more resources