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Review
. 2011 Dec 1;3(12):a011510.
doi: 10.1101/cshperspect.a011510.

Immunoreceptor signaling

Lawrence E Samelson  1
Affiliations
Review

Immunoreceptor signaling

Lawrence E Samelson. Cold Spring Harb Perspect Biol. .

Abstract

Antigens bind to immunoreceptors on the surface of T-cells and B-cells, activating signal transduction pathways that allow them to proliferate, differentiate, and synthesize effector molecules involved in the immune response.

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Figures

Figure 1.
Figure 1.
Early events in T cell and B cell receptor signaling.
Figure 2.
Figure 2.
T cell receptor signaling.
See this image and copyright information in PMC

References

    1. Andreotti AH, Schwartzberg PL, Joseph RE, Berg LJ 2010. T-cell signaling regulated by the Tec family kinase, Itk. Cold Spring Harb Perspect Biol 2: a002287. - PMC - PubMed
    1. Balagopalan L, Coussens NP, Sherman E, Samelson LE, Sommers CL 2010. The LAT story: A tale of cooperativity, coordination, and choreography. Cold Spring Harb Perspect Biol 2: a005512. - PMC - PubMed
    1. Bradshaw JM 2010. The Src, Syk, and Tec family kinases: Distinct types of molecular switches. Cell Signal 22: 1175–1184 - PubMed
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    1. Huang YH, Sauer K 2010. Lipid signaling in T-cell development and function. Cold Spring Harb Perspect Biol 2: a002428. - PMC - PubMed

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