Immunoreceptor signaling
- PMID: 22134888
- PMCID: PMC3225951
- DOI: 10.1101/cshperspect.a011510
Immunoreceptor signaling
Abstract
Antigens bind to immunoreceptors on the surface of T-cells and B-cells, activating signal transduction pathways that allow them to proliferate, differentiate, and synthesize effector molecules involved in the immune response.
Figures
Similar articles
-
The antigen receptors on B and T cells are not coupled to cytosolic phospholipase A2 activation and arachidonic acid release.Biochem Soc Trans. 1993 Nov;21(4):496S. doi: 10.1042/bst021496s. Biochem Soc Trans. 1993. PMID: 8132063 No abstract available.
-
Vav and the B cell signalosome.Nat Immunol. 2001 Jun;2(6):482-4. doi: 10.1038/88669. Nat Immunol. 2001. PMID: 11376331 No abstract available.
-
Lymphocyte signaling: adapting new adaptors.Curr Biol. 1998 Nov 5;8(22):R805-8. doi: 10.1016/s0960-9822(07)00505-2. Curr Biol. 1998. PMID: 9811598 Review.
-
Tec family kinases in lymphocyte signaling and function.Curr Opin Immunol. 2000 Jun;12(3):282-8. doi: 10.1016/s0952-7915(00)00088-1. Curr Opin Immunol. 2000. PMID: 10781397 Review.
-
Mechanisms determining a differential threshold for sensing Src family kinase activity by B and T cell antigen receptors.J Biol Chem. 2020 Sep 11;295(37):12935-12945. doi: 10.1074/jbc.RA120.013552. Epub 2020 Jul 14. J Biol Chem. 2020. PMID: 32665402 Free PMC article.
Cited by
-
Protein Clusters in Phosphotyrosine Signal Transduction.J Mol Biol. 2018 Oct 26;430(22):4547-4556. doi: 10.1016/j.jmb.2018.05.040. Epub 2018 Jun 2. J Mol Biol. 2018. PMID: 29870724 Free PMC article. Review.
-
The cell biology of HIV-1 latency and rebound.Retrovirology. 2024 Apr 5;21(1):6. doi: 10.1186/s12977-024-00639-w. Retrovirology. 2024. PMID: 38580979 Free PMC article. Review.
-
Immunological Disorders: Regulation of Ca2+ Signaling in T Lymphocytes.Adv Exp Med Biol. 2017;993:397-424. doi: 10.1007/978-3-319-57732-6_21. Adv Exp Med Biol. 2017. PMID: 28900926 Free PMC article. Review.
-
Uncovering a novel role of PLCβ4 in selectively mediating TCR signaling in CD8+ but not CD4+ T cells.J Exp Med. 2021 Jul 5;218(7):e20201763. doi: 10.1084/jem.20201763. Epub 2021 May 10. J Exp Med. 2021. PMID: 33970189 Free PMC article.
-
G-protein coupled receptor, PI3K and Rho signaling pathways regulate the cascades of Tau and amyloid-β in Alzheimer's disease.Mol Biomed. 2021 Jun 10;2(1):17. doi: 10.1186/s43556-021-00036-1. Mol Biomed. 2021. PMID: 35006431 Free PMC article. Review.
References
-
- Bradshaw JM 2010. The Src, Syk, and Tec family kinases: Distinct types of molecular switches. Cell Signal 22: 1175–1184 - PubMed
Publication types
MeSH terms
Substances
LinkOut - more resources
Full Text Sources