Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation
. 2011:4:371-5.
doi: 10.2147/DMSO.S25309. Epub 2011 Oct 13.

Clinical and behavioral factors associated with management outcome in hospitalized patients with diabetic foot ulcer

Zahra Yekta  1 , Reza Pourali, Rahim Nezhadrahim, Leila Ravanyar, Mohammad Ghasemi-Rad
Affiliations

Clinical and behavioral factors associated with management outcome in hospitalized patients with diabetic foot ulcer

Zahra Yekta et al. Diabetes Metab Syndr Obes. 2011.

Abstract

Objectives: Diabetic foot ulcer (DFU) has been linked to high mortality and morbidity in diabetic patients. In spite of the increasing prevalence of diabetes and its complications, this issue has not been adequately studied in Iran.

Materials and methods: In this cross-sectional study we attempt to describe the prevalence of diabetic foot amputation in patients admitted to our training hospitals in Urmia, Iran, and also to determine the associated demographic, behavioral, and clinical factors.

Results: Of 94 patients with DFU, 34 (32%) had amputation. Those with amputation were significantly older and were also less educated than those without amputation, had longer duration of diabetes (hence were more likely to suffer from complications), and had high-risk wounds plus a poor glycemic control. On logistic regression analysis two variables were associated with amputation: Wagner classification ≥3 and HbA(1c). On a receiver operating characteristics curve, the HbA(1c) cutoff point of 9.7% significantly discriminated to predict increasing risk of amputation.

Conclusion: Both glycemic control and promoting the knowledge of patients and health care professionals in order to diagnose DFU in the early stages and to prevent development of the high-grade wounds would be a significant step in reducing the burden of DFU and its effect on quality of life in Iran.

Keywords: amputation; diabetes mellitus; foot ulcer.

PubMed Disclaimer

Figures

Figure 1
Figure 1
Receiver operating characteristics (ROC) curve showing HbA1c and blood sugar (BS) in predicting overall amputation.
See this image and copyright information in PMC

References

    1. Tabatabaei Malazy O, Mohajeri-Tehrani MR, Pajouhi M, et al. Iranian diabetic foot research network. Adv Skin Wound Care. 2010;23:450–454. - PubMed
    1. Marston WA. Risk factors associated with healing chronic diabetic foot ulcers: the importance of hyperglycemia. Ostomy Wound Manage. 2006;52:26–28. 30, 32 passim. - PubMed
    1. Li X, Xiao T, Wang Y, et al. Incidence, risk factors for amputation among patients with diabetic foot ulcer in a Chinese tertiary hospital. Diabetes Res Clin Pract. 2011;93:26–30. - PubMed
    1. Bakker K. The year of the diabetic foot. Diabetes Voice. 2005;50:4–11.
    1. Yekta Z, Pourali R, Aghassi MR, et al. Assessment of self-care practice and its associated factors among diabetic patients in urban area of Urmia, northwest of Iran. Journal of Research in Health Sciences. 2011;11 - PubMed