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. 1978:(24 Pt 2):1019-25.

Potential for immunization against herpesvirus infections with plasma membrane vesicles

G R Pearson, R E Scott
  • PMID: 221369

Potential for immunization against herpesvirus infections with plasma membrane vesicles

G R Pearson et al. IARC Sci Publ (1971). 1978.

Abstract

Virus-free, membrane antigen (MA)-positive plasma membrane vesicles produced from herpesvirus saimiri-infected owl monkey cells were used as immunogens in cotton-top marmosets. Neutralizing antibodies as well as antibodies to MA and HVS-induced LA were induced following immunization of marmosets with these vesicles. Preliminary findings demonstrated that immunized marmosets were significantly less susceptible to tumour induction by HVS than control animals.

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