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Comment
. 2011 Dec 2;9(6):493-5.
doi: 10.1016/j.stem.2011.11.016.

Blood cells need glia, too: a new role for the nervous system in the bone marrow niche

Katja Brückner  1
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Blood cells need glia, too: a new role for the nervous system in the bone marrow niche

Katja Brückner. Cell Stem Cell. .
Free article

Abstract

Regulation of hematopoietic stem cell (HSC) dormancy by specific cell types in the hematopoietic niche remains poorly understood. Yamazaki et al. (2011) now report that nerve-associated nonmyelinating Schwann cells activate TGF-β to maintain dormant HSCs, suggesting that glia are novel players in the bone marrow niche.

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