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. 2012 Jun;42(6):532-5.
doi: 10.1007/s00595-011-0061-0. Epub 2011 Dec 3.

The prognostic nutritional index can be a prognostic indicator in colorectal carcinoma

Tadahiro Nozoe  1 , Mayuko Kohno, Tomohiro Iguchi, Emiko Mori, Takashi Maeda, Akito Matsukuma, Takahiro Ezaki
Affiliations

The prognostic nutritional index can be a prognostic indicator in colorectal carcinoma

Tadahiro Nozoe et al. Surg Today. 2012 Jun.

Abstract

Purpose: Preoperative assessments regarding a patient's immunological and nutritional condition are required to predict the outcomes of patients with malignant tumors. The aim of the current study was to clarify the significance of Onodera's prognostic nutritional index (OPNI), which can simply account for the immunological and nutritional conditions, in patients with colorectal carcinoma.

Methods: The correlations of the preoperative OPNI value with clinicopathological features were examined in 219 patients with colorectal carcinoma who had been surgically treated.

Results: Not only the tumor stage (P = 0.028) and venous invasion (P = 0.002), but also an OPNI of less than 40 (P = 0.002) were found to be independently correlated with a worse prognosis of patients with colorectal carcinoma.

Conclusion: The preoperative OPNI can be used as a simple prognostic indicator in colorectal carcinoma.

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