Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation
. 1990 Nov;64(11):5674-7.
doi: 10.1128/JVI.64.11.5674-5677.1990.

Oligomeric organization of gp120 on infectious human immunodeficiency virus type 1 particles

C D Weiss  1 , J A Levy, J M White
Affiliations

Oligomeric organization of gp120 on infectious human immunodeficiency virus type 1 particles

C D Weiss et al. J Virol. 1990 Nov.

Abstract

The oligomeric structure of the human immunodeficiency virus type 1 envelope glycoprotein (gp120) was examined by treating infectious virions with chemical cross-linking agents and subjecting the protein to sodium dodecyl sulfate-polyacrylamide gel electrophoresis and velocity centrifugation. Immunoblots of cross-linked samples revealed three gp120 bands and an approximately threefold shift in gp120 sedimentation. Our finding of cross-linking solely between gp120 suggests that the gp120 subunits are closely associated in the native envelope structure.

PubMed Disclaimer

References

    1. J Biol Chem. 1987 Aug 25;262(24):11519-23 - PubMed
    1. Annu Rev Biochem. 1987;56:365-94 - PubMed
    1. Virus Res. 1988 May;10(2-3):113-35 - PubMed
    1. Proc Natl Acad Sci U S A. 1988 Nov;85(22):8688-92 - PubMed
    1. Virology. 1988 Nov;167(1):299-301 - PubMed

Publication types

MeSH terms

Substances

LinkOut - more resources