[Chemotherapy of advanced ovarian cancer]

Abstract

Cisplatin containing chemotherapy has provoked an epic making revolution in the treatment of advanced ovarian cancer. However, the impact to the long-term survival is still discouraging. In this article, standard regime for first line chemotherapy, dose, administration method, routes, number of cycles and the second line chemotherapy which is the most embraced problem are described. Strategy for the treatment of advanced ovarian cancer would be continued until the development of new drugs which are effective comparable with cisplatin and have no cross resistance with cisplatin. In order to get significant improvement of 5 year survival, complete response by chemotherapy or complete resection by operation or by both is indispensable and partial response is not sufficient.