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. 2012 Jan;40(Database issue):D48-53.
doi: 10.1093/nar/gkr1202. Epub 2011 Dec 5.

GenBank

Dennis A Benson  1 , Ilene Karsch-Mizrachi, Karen Clark, David J Lipman, James Ostell, Eric W Sayers
Affiliations

GenBank

Dennis A Benson et al. Nucleic Acids Res. 2012 Jan.

Abstract

GenBank® is a comprehensive database that contains publicly available nucleotide sequences for more than 250,00 formally described species. These sequences are obtained primarily through submissions from individual laboratories and batch submissions from large-scale sequencing projects, including whole-genome shotgun (WGS) and environmental sampling projects. Most submissions are made using the web-based BankIt or standalone Sequin programs, and accession numbers are assigned by GenBank staff upon receipt. Daily data exchange with the European Nucleotide Archive (ENA) and the DNA Data Bank of Japan (DDBJ) ensures worldwide coverage. GenBank is accessible through the NCBI Entrez retrieval system, which integrates data from the major DNA and protein sequence databases along with taxonomy, genome, mapping, protein structure and domain information, and the biomedical journal literature via PubMed. BLAST provides sequence similarity searches of GenBank and other sequence databases. Complete bimonthly releases and daily updates of the GenBank database are available by FTP. To access GenBank and its related retrieval and analysis services, begin at the NCBI home page: www.ncbi.nlm.nih.gov.

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References

    1. Benson DA, Karsch-Mizrachi I, Lipman DJ, Ostell J, Sayers EW. GenBank. Nucleic Acids Res. 2010;38:D46–D51. - PMC - PubMed
    1. Leinonen R, Akhtar R, Birney E, Bower L, Cerdeno-Tarraga A, Cheng Y, Cleland I, Faruque N, Goodgame N, Gibson R, et al. The European Nucleotide Archive. Nucleic Acids Res. 2011;39:D28–D31. - PMC - PubMed
    1. Kaminuma E, Kosuge T, Kodama Y, Aono H, Mashima J, Gojobori T, Sugawara H, Ogasawara O, Takagi T, Okubo K, et al. DDBJ progress report. Nucleic Acids Res. 2011;39:D22–D27. - PMC - PubMed
    1. Sayers EW, Barrett T, Benson DA, Bolton E, Bryant SH, Canese K, Chetvernin V, Church DM, Dicuccio M, Federhen S, et al. Database resources of the National Center for Biotechnology Information. Nucleic Acids Res. 2012;40:D13–D25. - PMC - PubMed
    1. Shumway M, Cochrane G, Sugawara H. Archiving next generation sequencing data. Nucleic Acids Res. 2010;38:D870–D871. - PMC - PubMed

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