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. 2011 Nov;43(6):733-5.
doi: 10.4103/0253-7613.89840.

Azathioprine induced cholestatic hepatitis

Viju Moses  1 , Banumathi Ramakrishna, Kurien Thomas
Affiliations

Azathioprine induced cholestatic hepatitis

Viju Moses et al. Indian J Pharmacol. 2011 Nov.

Abstract

We report a case of cholestatic hepatitis developed one week after exposure to azathioprine. The subsequent prolonged cholestatic phase was followed by full clinical remission. Current knowledge on pathogenesis and epidemiology and the diagnostic challenges presented by this rare complication are discussed, followed by recommendations for monitoring and management.

Keywords: Adverse drug reaction; azathioprine; cholestatic hepatitis; hepatic; ursodiol.

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Conflict of interest statement

Conflict of Interest: None declared.

Figures

Figure 1
Figure 1
Perivenular canalicular cholestasis: bile plugs within dilated canaliculi (arrows) 400×- H&E
See this image and copyright information in PMC

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