Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation
Case Reports
. 2011 Sep;15(3):299-302.
doi: 10.4103/0973-029X.86693.

"Hybrid" lesion of the maxilla

S Sankaranarayanan  1 , S Srinivas, P Sivakumar, R Sudhakar, S Elangovan
Affiliations
Case Reports

"Hybrid" lesion of the maxilla

S Sankaranarayanan et al. J Oral Maxillofac Pathol. 2011 Sep.

Abstract

Juvenile ossifying fibroma is an uncommon benign but aggressive fibroosseous lesion that affects the craniofacial skeleton. Their distinct clinical and histopathological features warrant the lesion to be considered as a separate entity from other fibro-osseous group of lesions such as fibrous dysplasia and cemento ossifying fibroma. Concomitant development of secondary aneurysmal bone cyst may rarely occur, which makes the lesion more aggressive and difficult to treat. We report a case of a 6 year old girl who was diagnosed with aneurysmal bone cyst during her earlier presentation at a private hospital and was treated for the same. The lesion recurred within 6 months. The second incisional biopsy specimen revealed features of trabecular variant of juvenile ossifying fibroma along with areas of aneurysmal bone cyst.

Keywords: Hybrid lesion; aneurysmal bone cyst; juvenile ossifying fibroma; trabecular variant.

PubMed Disclaimer

Conflict of interest statement

Conflict of Interest: None declared.

Figures

Figure 1
Figure 1
Diffuse swelling over the left middle third of face
Figure 2
Figure 2
Intraoral swelling seen on the palate
Figure 3
Figure 3
OPG showing diffuse radiopacity in the left maxillary sinus region
Figure 4
Figure 4
Axial CT showing lesion in the left maxillary sinus with nasal septum deviation
Figure 5
Figure 5
Coronal CT revealing superior displacement of the left orbital floor
Figure 6
Figure 6
Immature bony trabeculae with peripheral osteoid (arrow) and adjacent area of hemorrhage (H) (H and E, 200×)
Figure 7
Figure 7
Section showing blood filled cavity (H and E, 200×)
Figure 8
Figure 8
Section showing multinucleated giant cells (arrow) close to extravasated red blood cells (C) (H and E, 400×)
See this image and copyright information in PMC

References

    1. Sun G, Chen X, Tang E, Li Z, Li J. Juvenile ossifying fibroma of the maxilla. Int J Oral Maxillofac Surg. 2007;36:82–5. - PubMed
    1. El-Mofty S. Psammomatoid and trabecular juvenile ossifying fibroma of the craniofacial skeleton: Two distinct clinicopathologic entities. Oral Surg Oral Med Oral Pathol Oral Radiol Endod. 2002;93:296–304. - PubMed
    1. Struthers PJ, Shear M. Aneurysmal bone cyst of jaws. II. Pathogenesis. Int J Oral Surg. 1984;13:92–100. - PubMed
    1. Nasser MJ. Psammomatoid ossifying fibroma with secondary aneurysmal bone cyst of frontal sinus. Childs Nerv Syst. 2009;25:1513–6. - PMC - PubMed
    1. Blayney AW, el Tayeb AA. The hybrid fibro osseous lesions. J Laryngol Otol. 1986;100:291–302. - PubMed

Publication types