Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation
. 2011 Apr 28;1(1):6.
doi: 10.1186/2045-9912-1-6.

Oxygen/ozone as a medical gas mixture. A critical evaluation of the various methods clarifies positive and negative aspects

Affiliations

Oxygen/ozone as a medical gas mixture. A critical evaluation of the various methods clarifies positive and negative aspects

Velio Bocci et al. Med Gas Res. .

Abstract

Besides oxygen, several other gases such as NO, CO, H2, H2S, Xe and O3 have come to age over the past few years. With regards to O3, its mechanisms of action in medicine have been clarified during the last two decades so that now a comprehensive framework for understanding and recommending ozone therapy in various pathologies is available. O3 used within the determined therapeutic window is absolutely safe and more effective than golden standard medications in numerous pathologies, like vascular diseases. However, ozone therapy is mostly in practitioners' hands and some recent developments for increasing cost effectiveness and speed of treatment are neither standardized, nor evaluated toxicologically. Hence, the aim of this article is to emphasize the need to objectively assess the pros and cons of oxygen/ozone as a medical gas mixture in the hope that ozone therapy will be accepted by orthodox medicine in the near future.

PubMed Disclaimer

References

    1. Nakao A, Sugimoto R, Billiar TR, McCurry KR. Therapeutic antioxidant medical gas. J Clin Biochem Nutr. 2009;44:1–13. doi: 10.3164/jcbn.08-193R. - DOI - PMC - PubMed
    1. Mocellin S, Bronte V, Nitti D. Nitric oxide, a double edged sword in cancer biology: Searching for therapeutic opportunities. Med Res Rev. 2007;27:317–352. doi: 10.1002/med.20092. - DOI - PubMed
    1. Li L, Hsu A, Moore PK. Actions and interactions of nitric oxide, carbon monoxide and hydrogen sulphide in the cardiovascular system and in inflammation--a tale of three gases! Pharmacol Ther. 2009;123:386–400. doi: 10.1016/j.pharmthera.2009.05.005. - DOI - PubMed
    1. Motterlini R, Mann BE, Foresti R. Therapeutic applications of carbon monoxide-releasing molecules. Expert Opin Investig Drugs. 2005;14:1305–1318. doi: 10.1517/13543784.14.11.1305. - DOI - PubMed
    1. Foresti R, Bani-Hani MG, Motterlini R. Use of carbon monoxide as a therapeutic agent: promises and challenges. Intensive Care Med. 2008;34:649–658. doi: 10.1007/s00134-008-1011-1. - DOI - PubMed