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. 2011 Dec 9;147(6):1220-1.
doi: 10.1016/j.cell.2011.11.046.

A partner evokes latent differences between Hox proteins

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A partner evokes latent differences between Hox proteins

Aseem Z Ansari et al. Cell. .
Free article

Abstract

Hox transcription factors bind highly related DNA sequences in vitro, yet they regulate different genes and play distinct roles in anterior-posterior patterning in animals. Slattery et al. report that a common cofactor, Exd, accentuates latent sequence specificities of all eight Hox proteins and directs binding to relevant sites across the genome.

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