Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation
. 1990 Oct;232(2):243-8.
doi: 10.1016/0027-5107(90)90130-v.

Metabolic activation of quercetin mutagenicity

R Vrijsen  1 , Y Michotte, A Boeyé
Affiliations

Metabolic activation of quercetin mutagenicity

R Vrijsen et al. Mutat Res. 1990 Oct.

Abstract

The mutagenicity of quercetin was reinvestigated using the Salmonella/microsome test. The mutagenicity of quercetin was enhanced by the cytosolic fraction of liver extract (S100), or by ascorbate, and even more by the complete liver supernatant (S9) in the presence of cofactors (NADP and glucose-6-phosphate). The formation of metabolites by the S9 enzymes was demonstrated by reverse-phase HPLC.

PubMed Disclaimer

LinkOut - more resources