ROCK in a stiff place
- PMID: 22158859
- DOI: 10.1126/scitranslmed.3003389
ROCK in a stiff place
Abstract
Understanding the molecular and cellular mechanisms involved in the progression of atherosclerosis has revealed a vital role for the Rho kinase (ROCK) pathway associated with stiffening of the underlying extracellular matrix (Huynh et al., this issue).
Comment on
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Age-related intimal stiffening enhances endothelial permeability and leukocyte transmigration.Sci Transl Med. 2011 Dec 7;3(112):112ra122. doi: 10.1126/scitranslmed.3002761. Sci Transl Med. 2011. PMID: 22158860 Free PMC article.
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