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. 1990 Oct;40(10):1621-3.
doi: 10.1212/wnl.40.10.1621.

Effect of plasmapheresis on serum and CSF autoantibody levels in CNS paraneoplastic syndromes

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Effect of plasmapheresis on serum and CSF autoantibody levels in CNS paraneoplastic syndromes

F Graus et al. Neurology. 1990 Oct.

Abstract

We compared the effect of plasmapheresis on antineuronal autoantibody titers in the serum and CSF of 3 patients with CNS paraneoplastic syndromes. Plasmapheresis reduced the serum autoantibody titer to 20% of the initial levels in the 3 patients, but the CSF autoantibody titer decreased only in the patient with severe damage of the blood-brain barrier.

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