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Case Reports
. 2011:2011:82-3.
doi: 10.1182/asheducation-2011.1.82.

Therapy for aplastic anemia

Amy E DeZern  1 , Eva C Guinan
Affiliations
Case Reports

Therapy for aplastic anemia

Amy E DeZern et al. Hematology Am Soc Hematol Educ Program. 2011.

Abstract

A 24-year-old man from Ecuador presents to your clinic with dyspnea on exertion, bruising, and petechiae. He is noted to be pancytopenic with ANC 430, hemoglobin 7.4 g/dL (reticulocyte count 0.9%), and platelets 18 000. His BM biopsy is hypocellular for age. Ultimately, he is diagnosed with severe aplastic anemia. He is the only child of 2 South American parents without any matches in the unrelated donor registry, including cord blood. He is red cell- and platelet transfusion-dependent. He has been recommended therapy with antithymocyte globulin and cyclosporine but declined it. He seeks recommendations about new alternatives to this regimen to improve his chance of response.

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References

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