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. 2011:3:24.
doi: 10.3410/M3-24. Epub 2011 Dec 1.

Alzheimer's - Looking beyond plaques

W Sue T Griffin  1
Affiliations

Alzheimer's - Looking beyond plaques

W Sue T Griffin. F1000 Med Rep. 2011.

Abstract

Mounting evidence shows that inflammation plays a critical role in causing Alzheimer's disease. Over the last few decades we have gone from a situation where inflammation was generally believed to have no role in the disease to the current picture where chronic activation of IL-1 inflammation has been shown to account for many of the hallmarks of the disease. This review is a personal account of the quest to prove that inflammation plays a critical role in causing Alzheimer's disease.

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References

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    2. F1000 factor 9

      Evaluated by W Sue Griffin 18 Nov 2011, Mark A Smith 01 Sep 2008

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