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. 2011 Winter;22(4):84-8.

A systematic review of strategies that increase the recruitment and retention of African American adults in genetic and genomic studies

Vanessa A Johnson  1 , Yolanda M Powell-Young, Elisa R Torres, Ida J Spruill
Affiliations

A systematic review of strategies that increase the recruitment and retention of African American adults in genetic and genomic studies

Vanessa A Johnson et al. ABNF J. 2011 Winter.

Abstract

Background: The National Institutes of Health mandates the inclusion of ancestrally diverse populations into federally funded biomedical and clinical trials research. However, low participation of ethnic minorities in genetics-genomics research continues to be one of the most difficult aspects of conducting human subjects research.

Objective: This systematic review was conducted to document effective recruitment strategies that increase participation in genetics-genomics studies.

Methods: Extensive literature search strategies were employed to locate and appraise relevant literature reporting original data in which strategies to recruit African American adults into genetics-genomics research studies had been evaluated.

Results: Six studies published up to July, 2011 were included. Informal recruitment strategies for initial contact appeared to have a more positive impact on increasing recruitment and participation numbers than formal mailings of letters and postcards. Another key stratagem identified was participant-recruiter like-ancestry. Other methods such as monetary incentives and support of the research project by community leaders were not as effective.

Conclusions: Some strategies bolstered recruitment rates while others did not. More research is needed to determine the efficacy of recruitment strategies with African Americans.

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Figures

Figure 1
Figure 1
Flow diagram of inclusion studies modified from Moher, D., Liberati, A., Tetzlaff, J., Altman, D.G., The PRISM Group (2009). Preferred reporting items for systematic review analysis: The PRISM statement. PLoS Med
See this image and copyright information in PMC

References

    1. Aliyu MH, Calkins ME, Swanson CL, Jr, Lyons PD, Savage RM, May R, PAARTNERS Study Group Project among african americans to explore risks for schizophrenia (PAARTNERS): Recruitment and assessment methods. Schizophrenia Research. 2006;87(1–3):32–44. - PubMed
    1. Bussey-Jones J, Garrett J, Henderson G, Moloney M, Blumenthal C, Corbie-Smith G. The role of race and trust in tissue/blood donation for genetic research. Genetics in Medicine: Official Journal of the American College of Medical Genetics. 2010;12(2):116–121. - PMC - PubMed
    1. Cabral DN, Nápoles-Springer AM, Miike R, McMillan A, Sison JD, Wrensch MR, Wiencke JK. Population-and community-based recruitment of African Americans and Latinos. American Journal of Epidemiology. 2003;158(3):272. - PubMed
    1. Centre for Reviews and Dissemination . Systematic reviews: CRD's guidance for undertaking reviews in health care. University of York NHS Centre for Reviews and Dissemination; Layerthorpe, York, UK: 2009.
    1. Chang MH, Ned RM, Hong Y, Yesupriya A, Yang Q, Liu T, Dowling NF. Race/Ethnic variation in the association of lipid-related genetic variants with blood lipids in the adult U.S. population. Circulation.Cardiovascular Genetics. 2011 - PubMed

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