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. 2011 Nov 10;7 Suppl 1(Suppl 1):S8.
doi: 10.1186/1710-1492-7-S1-S8.

Eosinophilic esophagitis

Stuart Carr  1 , Wade Watson
Affiliations

Eosinophilic esophagitis

Stuart Carr et al. Allergy Asthma Clin Immunol. .

Abstract

Eosinophilic esophagitis (EoE) is an atopic condition of the esophagus that has become increasingly recognized over the last decade. Diagnosis of the disorder is dependent on the patient's clinical manifestations and histologic findings on esophageal mucosal biopsies. Patients with eosinophilic esophagitis should be referred to both an allergist and gastroenterologist for optimal management, which may include dietary modifications, pharmacologic agents such as corticosteroids, leukotriene modifiers and biologics as well as mechanical dilatation of the esophagus. The epidemiology, pathophysiology, diagnosis, treatment, and prognosis of EoE are discussed in this review.

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Figures

Figure 1
Figure 1
Images of endoscopic features of EoE. A. White exudates Courtesy of Dr. Hien Huynh. B. Linear furrows Courtesy of Dr. Hien Huyn. C. Linear tear plus concentric rings Courtesy of Dr. Adrian Jones. D. Edema, furrows and exudates Courtesy of Dr. Adrian Jones.
Figure 2
Figure 2
Proposed algorithm for the diagnosis and management of EoE. EoE: eosinophilic esophagitis; PPI: proton pump inhibitor; GERD: gastrointestinal reflux disease; HPF: high power field; IgE: immunoglobulin E; IL5: interleukin 5
See this image and copyright information in PMC

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