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. 2012 Jan 27;75(1):82-7.
doi: 10.1021/np2007318. Epub 2011 Dec 13.

2-Arylbenzofuran, flavonoid, and tyrosinase inhibitory constituents of Morus yunnanensis

Xiao Hu  1 , Jin-Wei Wu, Meng Wang, Mei-Hua Yu, Qin-Shi Zhao, He-Yao Wang, Ai-Jun Hou
Affiliations

2-Arylbenzofuran, flavonoid, and tyrosinase inhibitory constituents of Morus yunnanensis

Xiao Hu et al. J Nat Prod. .

Abstract

Two novel 2-arylbenzofuran dimers, morusyunnansins A and B (1 and 2), two new biflavonoids, morusyunnansins C and D (3 and 4), two new flavans, morusyunnansins E and F (5 and 6), and four known flavans (7-10) were isolated from the leaves of Morus yunnanensis. Compounds 5-8 showed potent inhibitory effects on mushroom tyrosinase with IC(50) values ranging from 0.12 ± 0.02 to 1.43 ± 0.43 μM.

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