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. 2011;4(5):341-5.
doi: 10.1159/000333420. Epub 2011 Oct 14.

Risk factors for overweight and diabetes mellitus in residential psychiatric patients

Evert J Mookhoek  1 , Willem A de Vries, Johannes E J M Hovens, Jacobus R B J Brouwers, Anton J M Loonen
Affiliations

Risk factors for overweight and diabetes mellitus in residential psychiatric patients

Evert J Mookhoek et al. Obes Facts. 2011.

Abstract

Objective: To investigate the prevalence of and risk factors for overweight and diabetes mellitus in long-stay psychiatric inpatients.

Method: Statistical analysis of data collected from medical, laboratory, and pharmacy files.

Results: 80% of the 256 patients were suffering from schizophrenia or other psychotic disorders. The prevalence of diabetes mellitus was 15%. The prevalence of a disturbed glucose tolerance was 14%. Severe overweight (BMI > 30) was positively associated with the use of clozapine (odds ratio (OR) = 2.7; 95% confidence interval (CI): 1.31-5.75), but negatively with the diagnosis schizophrenia (OR = 0.4; 95% CI: 0.22-0.88). Diabetes mellitus was associated with severe overweight (OR = 3.5; 95% CI: 1.57-7.69). Caucasian patients were at a lower risk for diabetes mellitus (OR = 0.2; 95% CI: 0.08-0.54).

Conclusions: In residential psychiatric patients, diabetes mellitus is especially associated with overweight and non-Caucasian origin. In this survey, the use of clozapine was associated with overweight, but not directly with diabetes mellitus. Diabetes mellitus is highly prevalent, which calls for screening for diabetes mellitus at regular intervals.

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References

    1. Cassidy F, Ahearn E, Carroll BJ. Elevated frequency of diabetes mellitus in hospitalized manic-depressive patients. Am J Psychiatry. 1999;156:1417–1420. - PubMed
    1. Bushe C, Holt R. Prevalence of diabetes and impaired glucose tolerance in patients with schizophrenia. Br J Psychiatry. 2004;184((suppl 47)):s67–s71. - PubMed
    1. Freeman H, Rodnick EH, Shakow D, Lebeaux T. The carbohydrate tolerance of mentally disturbed soldiers. Psychosom Med. 1944;6:311–317.
    1. Kohen D. Diabetes mellitus and schizophrenia: historical perspective. Br J Psychiatry. 2004;184((suppl 47)):s64–s66. - PubMed
    1. Nimwegen LJM van, Storosum JG, Blumer RME, Allick G, Venema HW, de Haan L, Becker H, van Amelsvoort T, Ackermans MT, Fliers E, Serlie MJ, Sauerwein HP, Hepatic insulin resistance in antipsychotic naïve schizophrenic patients. stable isotope studies of glucose metabolism. J Clin Endocrinol Metab. 2008;93:572–577. - PubMed

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