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Editorial
. 2011 Sep;43(3):101-2.

"See, feel, change"

Editorial

"See, feel, change"

Robert C Groom. J Extra Corpor Technol. 2011 Sep.
No abstract available

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Figures

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Robert Groom
Figure 1.
Figure 1.
Bubble obstructing end-arterial flow in a cerebral vessel with a diameter of 30 to 60 μm, causing distal ischemia. The obstruction causes the metabolic processes of neurons to fail. Sodium and water enter the neuron, and cytotoxic edema develops. The surface of the bubble generates a foreign-body response through cellular and humoral immune mechanisms. The bubble also mechanically irritates the arterial endothelium. Both processes result in vasogenic edema and greater impairment of perfusion. The neuronal injury extends beyond the area of obstruction. (Reprinted with permission from N Engl J Med 2000;342: 476–823)

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References

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