Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation
. 2011 Sep-Oct;56(5):37-40.

[Antiherpesviral activity of acycloguanosine H-phosphonate in experiments using laboratory animals]

[Article in Russian]
V L Andronova, G A Galegov, M V Ias'ko, M K Kukhanova, S N Kochetkov, Iu S Skoblov
  • PMID: 22171477

[Antiherpesviral activity of acycloguanosine H-phosphonate in experiments using laboratory animals]

[Article in Russian]
V L Andronova et al. Vopr Virusol. 2011 Sep-Oct.

Abstract

A study of the antiherpesviral activity of acycloguanosine (ACG) H-phosphonate (ACG-P) on a model of fatal herpesvirus infection in inbred BALB/c albino mice has established that ACG-P reduces death rates in the animals, considerably increases their average lifespan, and significantly decreases brain virus titers with both 60% mortality in the control and 92% mortality in the control group. There was also a significant inhibition of herpes simplex virus type 1 (HSV-1) replication in the brain tissue of animals receiving ACG-P on a model of ACG-resistant HSV-1/L2/RACG(TK-).

PubMed Disclaimer

MeSH terms

LinkOut - more resources