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. 2011 Dec 15:4:543.
doi: 10.1186/1756-0500-4-543.

Clinical outcome of skin yaws lesions after treatment with benzathinebenzylpenicillin in a pygmy population in Lobaye, Central African Republic

Alexandre Manirakiza  1 , Susana Vilas Boas, Narcisse Beyam, Germain Zadanga, François Xavier Konamna, Siméon P Njuimo, Rémi Laganier
Affiliations

Clinical outcome of skin yaws lesions after treatment with benzathinebenzylpenicillin in a pygmy population in Lobaye, Central African Republic

Alexandre Manirakiza et al. BMC Res Notes. .

Abstract

Background: Yaws is a bacterial skin and bone infectious disease caused by Treponema pallidum pertenue. It is endemic, particularly among pygmies in Central African Republic. To assess the clinical cure rate after treatment with benzathinepenicillin in this population, we conducted a cohort survey of 243 patients in the Lobaye region.

Findings and conclusion: The rate of healing of lesions after 5 months was 95.9%. This relatively satisfactory level of therapeutic response implies that yaws could be controlled in the Central African Republic. Thus, reinforcement of the management of new cases and of contacts is suggested.

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Figures

Figure 1
Figure 1
Study location, Mongoumba, Central African Republic.
Figure 2
Figure 2
Active yaws lesions, Mongoumba, Central African Republic, December 2007 (photograph by S.V. Boas).
Figure 3
Figure 3
Age distribution by stage of yaws in 243 patients, Central African Republic, December 2007-September 2008.
Figure 4
Figure 4
Clinical healing after treatment of yaws in 243 patients, Central African Republic, December 2007-September 2008.
See this image and copyright information in PMC

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