Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation
. 2011 Dec;17(12):2309-12.
doi: 10.3201/eid1712.110371.

Hepatitis E virus antibodies in blood donors, France

Jean-Michel Mansuy  1 , Richard Bendall, Florence Legrand-Abravanel, Karine Sauné, Marcel Miédouge, Vic Ellis, Henri Rech, François Destruel, Nassim Kamar, Harry R Dalton, Jacques Izopet
Affiliations

Hepatitis E virus antibodies in blood donors, France

Jean-Michel Mansuy et al. Emerg Infect Dis. 2011 Dec.

Abstract

Using a validated sensitive assay, we found hepatitis E virus (HEV) IgG in 52.5% of voluntary blood donors in southwestern France. This finding suggests HEV is highly endemic to this region. The high HEV prevalence may reflect local dietary practices, such as eating uncooked pork and game products.

PubMed Disclaimer

Figures

Figure 1
Figure 1
Prevalence of hepatitis E virus (HEV) IgG in 512 blood donors by age group, Midi-Pyrénées region, France, 2003–2004.
Figure 2
Figure 2
Distribution of optical density/cut off ratios for hepatitis E virus IgG in positive and negative samples from 512 blood donors, Midi-Pyrénées region, France, 2003–2004. Whiskers represent percentiles.
See this image and copyright information in PMC

References

    1. Dalton HR, Bendall R, Ijaz S, Banks M. Hepatitis E: an emerging infection in developed countries. Lancet Infect Dis. 2008;8:698–709. 10.1016/S1473-3099(08)70255-X - DOI - PubMed
    1. Mansuy JM, Legrand-Abravanel F, Calot JP, Peron JM, Alric L, Agudo S, et al. High prevalence of anti-hepatitis E virus antibodies in blood donors from south west France. J Med Virol. 2008;80:289–93. 10.1002/jmv.21056 - DOI - PubMed
    1. Boutrouille A, Bakkali-Kassimi L, Cruciere C, Pavio N. Prevalence of anti-hepatitis E virus antibodies in French blood donors. J Clin Microbiol. 2007;45:2009–10. 10.1128/JCM.00235-07 - DOI - PMC - PubMed
    1. Herremans M, Bakker J, Duizer E, Vennema H, Koopmans MP. Use of serological assays for diagnosis of hepatitis E virus genotype 1 and 3 infections in a setting of low endemicity. Clin Vaccine Immunol. 2007;14:562–8. 10.1128/CVI.00231-06 - DOI - PMC - PubMed
    1. Bendall R, Ellis V, Ijaz S, Ali R, Dalton H. A comparison of two commercially available anti-HEV IgG kits and a re-evaluation of anti-HEV IgG seroprevalence data in developed countries. J Med Virol. 2010;82:799–805. 10.1002/jmv.21656 - DOI - PubMed

Publication types

MeSH terms

LinkOut - more resources