Going with the flow: an elegant model for symmetry breaking
- PMID: 22172666
- DOI: 10.1016/j.devcel.2011.11.015
Going with the flow: an elegant model for symmetry breaking
Abstract
The entry of the sperm centrosome polarizes the anterior-posterior axis of the C. elegans zygote by inducing the formation of complementary cortical Par protein domains. Recent papers from the Seydoux and Grill laboratories (Goehring et al., 2011b and Motegi et al., 2011) reveal how two different symmetry-breaking mechanisms produce the same final pattern through interactions between Par proteins.
Copyright © 2011 Elsevier Inc. All rights reserved.
Comment on
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Microtubules induce self-organization of polarized PAR domains in Caenorhabditis elegans zygotes.Nat Cell Biol. 2011 Oct 9;13(11):1361-7. doi: 10.1038/ncb2354. Nat Cell Biol. 2011. PMID: 21983565 Free PMC article.
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Polarization of PAR proteins by advective triggering of a pattern-forming system.Science. 2011 Nov 25;334(6059):1137-41. doi: 10.1126/science.1208619. Epub 2011 Oct 20. Science. 2011. PMID: 22021673
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