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Comment
. 2011 Dec 13;20(6):695-7.
doi: 10.1016/j.ccr.2011.11.018.

Many tumors in one: a daunting therapeutic prospect

Chibawanye I Ene  1 , Howard A Fine
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Many tumors in one: a daunting therapeutic prospect

Chibawanye I Ene et al. Cancer Cell. .
Free article

Abstract

In this issue of Cancer Cell, Snuderl and coworkers demonstrate intratumoral genetic heterogeneity in glioblastoma based on in situ amplification of distinct genomic loci within individual cells in a mutually exclusive pattern. These findings may herald trouble for current targeted therapies but provide insights for future treatment strategies.

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