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Case Reports
. 2011 Apr;26(2):102-3.
doi: 10.4103/0972-3919.90263.

Crossed cerebellar diaschisis on F-18 FDG PET/CT

Affiliations
Case Reports

Crossed cerebellar diaschisis on F-18 FDG PET/CT

Kanhaiya Lal Agrawal et al. Indian J Nucl Med. 2011 Apr.

Abstract

Diaschisis is the inhibition of function produced by focal disturbances in a portion of the brain at a distance from original site of injury. Many studies using brain SPECT (single-photon emission computed tomography) have demonstrated crossed cerebellar diaschisis (CCD) in patients with cerebral cortical infarct. We report a case of cerebrovascular accident involving the left middle cerebral artery territory. PET/CT performed one month after stroke showed hypometabolism in the left cerebral hemisphere with hypometabolism of the contralateral cerebellum. The finding of diminished glucose metabolism in the contralateral cerebellum represents CCD.

Keywords: Crossed cerebellar diaschisis; PET/CT; stroke.

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Conflict of interest statement

Conflict of Interest: None declared.

Figures

Figure 1
Figure 1
MRI of the brain (a) showing altered signal intensity in the left parietal, temporal cortices and left basal ganglia. Both cerebellar hemispheres (b) are normal
Figure 2
Figure 2
Transaxial sections at basal ganglia level (a) PET (b) CT (c) fused PET/CT showing FDG hypometabolism in the frontal, parietal and temporal cortices and basal ganglia on the left side region corresponding to a well defined hypodense area on CT
Figure 3
Figure 3
Transaxial sections at the cerebellar level (a) PET (b) CT (c) fused PET/CT showing diffuse FDG hypometabolism in the right cerebellar hemisphere with CT showing no morphological abnormality
Figure 4
Figure 4
Maximum intensity projection image showing right cerebellar hypometabolism

References

    1. Baron JC, Bousser MG, Comar D, Castaigne P. Crossed cerebellar diaschisis in human supratentorial brain infarction. Trans Am Neurol Assoc. 1981;105:459–61. - PubMed
    1. Pantano P, Baron JC, Samson Y, Bousser MG, Derouesne C, Comar D. Crossed cerebellar diaschisis: Further studies. Brain. 1986;109:677–94. - PubMed
    1. Ito H, Kanno I, Shimosegawa E, Tamura H, Okane K, Hatazawa J. Hemodynamic changes during neural deactivation in human brain: A positron emission tomography study of crossed cerebellar diaschisis. Ann Nucl Med. 2002;16:249–54. - PubMed
    1. Wiesendanger M. Constantin von Monakow (1853–1930): A pioneer in interdisciplinary brain research and a humanist. Comptes Rendus Biologies. 2006;329:406–18. - PubMed
    1. Otte A, Roelcke U, von Ammon K, Hausmann O, Maguire RP, Missimer J, et al. Crossed cerebellar diaschisis and brain tumor biochemistry studied with positron emission tomography, [F18] fluorodeoxyglucose and [11 C] methionine. J Neurol Sci. 1998;156:73–7. - PubMed

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