Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation
Case Reports
. 2011 Apr;26(2):109-11.
doi: 10.4103/0972-3919.90266.

Post transplant urinary tract infection in Autosomal dominant polycystic kidney disease a perpetual diagnostic dilema - 18-fluorodeoxyglucose - Positron emission computerized tomography - A valuable tool

Vv Sainaresh  1 , Sh Jain, Hv Patel, Pr Shah, Av Vanikar, Hl Trivedi
Affiliations
Case Reports

Post transplant urinary tract infection in Autosomal dominant polycystic kidney disease a perpetual diagnostic dilema - 18-fluorodeoxyglucose - Positron emission computerized tomography - A valuable tool

Vv Sainaresh et al. Indian J Nucl Med. 2011 Apr.

Abstract

Urinary tract infection (UTI) is the most common infection contracted by renal allograft recipients. In patients of autosomal dominant polycystic kidney disease (ADPKD), cyst infection presents a complex diagnostic and therapeutic challenge especially in the post transplant period. Accurate diagnosis forms the cornerstone in salvaging the graft from potentially catastrophic outcome. We describe a case of xanthogranulomatous pyelonephritis (XPN) in the native kidney in a patient of post transplant ADPKD which presented as frequently relapsing UTI with graft dysfunction where in accurate diagnosis was made possible with the aid of 18-fluorodeoxyglucose (FDG) - Positron emission computerized tomography (PET/CT).

Keywords: ADPKD; PET/CT; UTI; transplantation; xanthogranulomatous pyelonephritis.

PubMed Disclaimer

Conflict of interest statement

Conflict of Interest: None declared.

Figures

Figure 1
Figure 1
PET/CT scan showing strong FDG uptake into postero inferior part of right native kidney (arrow)
Figure 2
Figure 2
Gross section of Right kidney showing xanthogranulomatous area (arrow)
Figure 3
Figure 3
Light micrograph showing an interstitial infiltrate composed of neutrophils, mononuclear cells, and, most characteristically, lipid-laden macrophages (arrow). (H and E, ×100)
See this image and copyright information in PMC

References

    1. De Souza RM, Olsburgh J. Urinary tract infection in the renal transplant patient. Nat Clin Pract Nephrol. 2008;4:252–64. - PubMed
    1. Chuang CK, Lai MK, Chang PL, Huang MH, Chu SH, Wu CJ, et al. Xanthogranulomatous pyelonephritis experience in 36 cases. J Urol. 1992;147:333–6. - PubMed
    1. Zorzos I, Moutzouris V, Korakiantis G, Katsou G. Analysis of 39 cases xanthogranulomatous pyelonephritis with emphasis on CT findings. Scand J Urol Nephrol. 2003;37:342–7. - PubMed
    1. Parsons MA, Harris SC, Grainger RG, Ross B, Smith JA, Williams JL. Fistula and sinus formation in xanthogranulomatous pyelonephritis.A clinicopathological review and report of four cases. Br J Urol. 1986;58:488–93. - PubMed
    1. Hitti W, Drachenberg C, Cooper M, Schweitzer E, Cangro C, Klassen D, et al. Xanthogranulomatous pyelonephritis in a renal allograft associated with xanthogranulomatous diverticulitis: Report of the first case and review of the literature. Nephrol Dial Transplant. 2007;22:3344–7. - PubMed

Publication types