Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation
Case Reports
. 2011:2011:980257.
doi: 10.1155/2011/980257. Epub 2011 Nov 17.

Leiomyosarcoma of bone: a case report

Andreas Frings  1 , Andreas Leithner, Bernadette Liegl-Atzwanger
Affiliations
Case Reports

Leiomyosarcoma of bone: a case report

Andreas Frings et al. Case Rep Med. 2011.

Abstract

The aim of this paper is to present clinicopathologic features and immunohistochemical findings of a primary leiomyosarcoma of bone occurring in the proximal femur of a 46-year-old Caucasian male patient. Each case report on this exceedingly rare entity contributes to the notion of this disease.

PubMed Disclaimer

Figures

Figure 1
Figure 1
Radiographs of the patient's right femur: (a) preoperative, an expanding lytic lesion (10 cm in max. diameter) located in the right proximal femur with extension into the proximal shaft, (b) two months after limb salvage surgery followed by endoprosthetic replacement.
Figure 2
Figure 2
The explant shows a proximal femur measured 25 cm in length, a tumor of 10 cm in max. dimension and predominantly grey-white appearance occupies the medullary cavity.
Figure 3
Figure 3
Histologic workup of the tumor tissue: (a) HE, (b) HE, (c) SMA, (d) Desmin.
See this image and copyright information in PMC

References

    1. Somerhausen NDSA, Cin PD. Smooth muscle tumours. In: Fletcher CDM, Unni KK, Mertens F, editors. Pathology and Genetics of Tumours of Soft Tissue and Bone. World Health Organization Classification of Tumours. Lyon, France: IARC Press; 2002. p. 131.
    1. Petra M, Gibbons CLMH, Athanasou NA. Leiomyosarcoma of bone arising in association with a bone infarct. Sarcoma. 2002;6(1):47–50. - PMC - PubMed
    1. Evans D, Sanarkin NG. Primary leiomyosarcoma of bone. Journal of Pathology & Bacteriology. 1965;90:348–350. - PubMed
    1. Jundt G, Moll C, Nidecker A, Schilt R, Remagen W. Primary leiomyosarcoma of bone: report of eight cases. Human Pathology. 1994;25(11):1205–1212. - PubMed
    1. Johnson S, Tetu B, Ayala AG, Chawla SP. Chondrosarcoma with additional mesenchymal component (dedifferentiated chondrosarcoma): I. A clinicopathologic study of 26 cases. Cancer. 1986;58(2):278–286. - PubMed

Publication types

LinkOut - more resources