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Review
. 2012:2012:374047.
doi: 10.1155/2012/374047. Epub 2011 Dec 11.

Preeclampsia, hypoxia, thrombosis, and inflammation

Amir A Shamshirsaz  1 , Michael Paidas, Graciela Krikun
Affiliations
Review

Preeclampsia, hypoxia, thrombosis, and inflammation

Amir A Shamshirsaz et al. J Pregnancy. 2012.

Abstract

Reductions in uteroplacental flow initiate a cascade of molecular effects leading to hypoxia, thrombosis, inflammation, and endothelial cell dysfunction resulting in untoward pregnancy outcomes. In this review, we detail these effects and their relationship to preeclampsia (PE) and intrauterine growth restriction (IUGR).

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