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. 2012 Feb;206(2):134.e1-8.
doi: 10.1016/j.ajog.2011.10.878. Epub 2011 Nov 7.

Prevalence, trends, and outcomes of chronic hypertension: a nationwide sample of delivery admissions

Brian T Bateman  1 , Pooja Bansil, Sonia Hernandez-Diaz, Jill M Mhyre, William M Callaghan, Elena V Kuklina
Affiliations

Prevalence, trends, and outcomes of chronic hypertension: a nationwide sample of delivery admissions

Brian T Bateman et al. Am J Obstet Gynecol. 2012 Feb.

Abstract

Objective: We sought to define the prevalence, trends, and outcomes of primary and secondary chronic hypertension in a population-based sample of deliveries.

Study design: An estimated 56,494,634 deliveries were identified from the 1995 through 2008 Nationwide Inpatient Sample. The association of primary and secondary chronic hypertension with adverse fetal and maternal outcomes was evaluated using regression modeling and adjusted population-attributable fractions were calculated.

Results: During the study period, the prevalence of primary and secondary hypertension increased from 0.90% in 1995 through 1996 to 1.52% in 2007 through 2008 (P for trend < .001) and from 0.07% to 0.24% (P for trend < .001), respectively. The population-attributable fraction for chronic hypertension was considerable for many maternal adverse outcomes, including acute renal failure (21%), pulmonary edema (14%), preeclampsia (11%), and in-hospital mortality (10%).

Conclusion: Primary and secondary chronic hypertension were both strongly associated with adverse pregnancy outcomes and accounted for a substantial fraction of maternal morbidity. Prioritizing research efforts in this area is needed.

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Figures

Figure 1
Figure 1
Trends in age-adjusted prevalence of chronic, primary, and secondary hypertension, 1995-1996 through 2007-2008, Nationwide Inpatient Sample
Figure 2
Figure 2
Trends in age-adjusted prevalence of chronic hypertension with associated co-morbid conditions, 1995-1996 through 2007-2008, Nationwide Inpatient Sample
See this image and copyright information in PMC

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