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Review
. 2012 Mar;160(3):366-71.
doi: 10.1016/j.jpeds.2011.11.024. Epub 2011 Dec 16.

Ciliopathies: the central role of cilia in a spectrum of pediatric disorders

Thomas W Ferkol  1 , Margaret W Leigh
Affiliations
Review

Ciliopathies: the central role of cilia in a spectrum of pediatric disorders

Thomas W Ferkol et al. J Pediatr. 2012 Mar.
No abstract available

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Figures

Figure
Figure
A, Schematic diagram showing the structural elements of motile “9+2”, motile “9+0”, and non-motile “9+0” ciliary axonemes. B, Classification and sites of different cilia, showing the coordinated synchronous motion of motile “9+2” cilia, the rotary motion of motile “9+0” nodal monocilium, and non-motile “9+0” primary monocilium (modified from Leigh, et al [1]).
See this image and copyright information in PMC

References

    1. Leigh MW, Pittman JE, Carson JL, Ferkol TW, Dell SD, Davis SD, Knowles MR, Zariwala MA. Clinical and genetic aspects of primary ciliary dyskinesia and Kartagener syndrome. Genet Med. 2009;11:473–87. - PMC - PubMed
    1. Cardenas-Rodriguez M, Badano JL. Ciliary biology: understanding the cellular and genetic basis of human ciliopathies. Am J Med Genet C Semin Med Genet. 2009;151:263–80. - PubMed
    1. Satir P, Pedersen LB, Christensen ST. The primary cilium at a glance. J Cell Sci. 2010;123:499–503. - PMC - PubMed
    1. Badano JL, Mitsuma N, Beales PL, Katsanis N. The ciliopathies: an emerging class of human genetic disorders. Ann Rev Genomics Hum Genet. 2006;7:125–148. - PubMed
    1. Tobin JL, Beales PL. The nonmotile ciliopathies. Genet Med. 2009;11:386–402. - PubMed

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