Transcriptional activators and activation mechanisms
- PMID: 22180087
- PMCID: PMC4712173
- DOI: 10.1007/s13238-011-1101-7
Transcriptional activators and activation mechanisms
Abstract
Transcriptional activators are required to turn on the expression of genes in a eukaryotic cell. Activators bound to the enhancer can facilitate either the recruitment of RNA polymerase II to the promoter or its elongation. This article examines a few selected issues in understanding activator functions and activation mechanisms.
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