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Review
. 2011 Dec 20;8(2):74-6.
doi: 10.1038/nrendo.2011.226.

Epigenetics and metabolism in 2011: Epigenetics, the life-course and metabolic disease

Peter D Gluckman  1
Affiliations
Review

Epigenetics and metabolism in 2011: Epigenetics, the life-course and metabolic disease

Peter D Gluckman. Nat Rev Endocrinol. .

Abstract

Clinical and experimental studies suggest that early life experiences, perhaps spanning multiple generations, affect lifelong risk of metabolic dysfunction through epigenetic mechanisms. Data published in 2011 suggest that epigenetic analysis could potentially have utility as a marker of early metabolic pathology and might enable early life prophylaxis.

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