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Case Reports
. 2012 Feb 21;184(3):E201.
doi: 10.1503/cmaj.111475. Epub 2011 Dec 19.

Sickle cell disease

Edwin Bölke  1 , Axel Scherer
Affiliations
Case Reports

Sickle cell disease

Edwin Bölke et al. CMAJ. .
No abstract available

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Figures

Figure 1:
Figure 1:
A) Sagittal fat-suppressed t2-weighted magnetic resonance image of the right proximal femur showing spotty areas of high signal intensity (arrowheads), representing areas of maturing bone infarcts. (B) Axial computed tomography (CT) scan of the upper abdomen obtained after administration of intravenous contrast medium showing an enlarged liver with heterogeneous enhancement (arrows), a finding compatible with liver infarction. (C) Axial CT image (bone window) of the upper skull showing striated bone caused by diploic space widening (asterisk). (D) Axial CT image of the brain showing a space-occupying epidural hematoma, most likely caused by expansion of hematopoietic tissue and disruption of bony margins with bleeding into the epidural space (arrows). (E) Microscopic image of sickle red blood cells.
See this image and copyright information in PMC

References

    1. Akinsheye I, Solovieff N, Ngo D, et al. Fetal hemoglobin in sickle cell anemia: molecular characterization of the unusually high fetal hemoglobin phenotype in African Americans. Am J Hematol 2011. October 14 [Epub ahead of print]. - PMC - PubMed
    1. Rosenthal PJ. Lessons from sickle cell disease in the treatment and control of malaria. N Engl J Med 2011;364:2549–51 - PubMed
    1. Clark TD, Greenhouse B, Njama-Meya D, et al. Factors determining the heterogeneity of malaria incidence in children in Kampala, Uganda. J Infect Dis 2008;198:393–400 - PubMed

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