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Comment
. 2011 Dec 19;208(13):2565-6.
doi: 10.1084/jem.20112203.

The nature of circulating CD27+CD43+ B cells

Martin Perez-Andres, Christina Grosserichter-Wagener, Cristina Teodosio, Jacques J M van Dongen, Alberto Orfao, Menno C van Zelm
Comment

The nature of circulating CD27+CD43+ B cells

Martin Perez-Andres et al. J Exp Med. .
No abstract available

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Figures

Figure 1.
Figure 1.
Flow cytometric analysis of CD19+CD27+CD43+ cells in human neonatal cord blood, peripheral blood, and tonsil samples. (A–C) CD27+CD43+ cells (red) were defined within CD19+ lymphocytes (blue; left plots). Where illustrative, the CD19− lymphocytes (T cells and NK cells) are shown in yellow. Samples were also stained with anti-CD3, anti-CD5, and anti-CD38 as indicated. The right plots only display CD19+CD3− events. Data are representative of 4 cord blood, 27 blood, and 7 tonsil samples. (D) Frequencies of CD27+CD43+ cells among CD19+ cells in neonatal cord blood and peripheral blood samples from individual children and adults of indicated ages. The relative contributions of CD3+ T cells, CD3−CD38hi plasma cells, and CD3−CD38low B lymphocytes are indicated for each individual. (E) Frequencies of CD43+, CD43−IgM+, and CD43-IgM− cells among CD19+CD27+CD3−CD38low cells within the blood of healthy adults. Individual frequencies are shown in gray and the median is indicated with a red bar. IgM expression was detected with a monoclonal IgM-HorizonV450 antibody (clone G20-127).
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