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. 2012:2012:321545.
doi: 10.1155/2012/321545. Epub 2011 Nov 30.

A Population-Based Study of Meconium Aspiration Syndrome in Neonates Born between 37 and 43 Weeks of Gestation

C Fischer  1 , C Rybakowski, C Ferdynus, P Sagot, J B Gouyon
Affiliations

A Population-Based Study of Meconium Aspiration Syndrome in Neonates Born between 37 and 43 Weeks of Gestation

C Fischer et al. Int J Pediatr. 2012.

Abstract

The epidemiology of meconium aspiration syndrome (MAS) in term neonates is described in a population-based retrospective study of data recorded for all births from 2000 to 2007 in a French region (Burgundy). Of the 132 884 eligible term newborns, the rate of meconium-stained amniotic fluid (MSAF) was 7.93%. The prevalence of severe MAS was 0.067% in the overall population. MAS rate was 0.11% at 37-38 weeks of gestation (WG), 0.20% at 39-41 WG, and 0.49% at 42-43 WG. Factors independently associated with severe MAS were identified by a case-control study, that is, thick meconium amniotic fluid, fetal tachycardia, Apgar score ≤3 at 1 minute, and birth in a level III facility. Our results confirm the high prevalence of MSAF after 37 WG but also show the low frequency of severe MAS in a period corresponding to the new international recommendations on the management of birth with MSAF.

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Figures

Figure 1
Figure 1
Rates of meconium-stained amniotic fluid (MSAF) in the global population and rate of meconium aspiration syndrome (MAS) amongst MSAF according to gestational age in term and postterm deliveries.
Figure 2
Figure 2
Rates of meconium aspiration syndrome (MAS) in the global population according to gestational age in term and post-term deliveries.
See this image and copyright information in PMC

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