Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation
. 2010 Dec;9(4):389-95.
doi: 10.1007/s12663-010-0132-6. Epub 2011 Mar 11.

Epidemiological Analysis of Cleft Lip and/or Palate by Cleft Pattern

Epidemiological Analysis of Cleft Lip and/or Palate by Cleft Pattern

Yoshikazu Nagase et al. J Maxillofac Oral Surg. 2010 Dec.

Abstract

Objectives: To analyze gender differences in cleft pattern by the clinical statistical study of Japanese patients with cleft lip and/or cleft palate.

Study design: Cleft pattern modeling was used to analyze 782 patients with cleft lip and/or cleft palate (417 males and 365 females) who had been examined at the Cleft Lip and Palate Center, Aichi-Gakuin University Hospital, and whose details could be confirmed. Relationships between gender and cleft type were analyzed with chi-squared test.

Results: A comparison of gender differences by cleft type revealed that a greater percentage of males had milder cleft lip, cleft lip and palate, or cleft palate, whereas the percentage of females tended to be greater as cleft severity increased.

Conclusions: Modeling of cleft patterns enables more detailed classification of cleft lip and palate, and can lead to a greater understanding of pathology.

Keywords: Cleft lip; Cleft palate; Clinical statistics; Congenital malformation.

PubMed Disclaimer

Figures

Fig. 1
Fig. 1
The model for cleft lip and/or palate divided into 16 regions
Fig. 2
Fig. 2
The model for cleft of cleft lip and/or palate divided into 35 regions
Fig. 3
Fig. 3
a Sexual difference (cleft lip). b Sexual difference (cleft lip and palate). c Sexual difference (cleft palate)

References

    1. Natsume N, Suzuki T, Kawai T. Clinical analysis of the cleft patterns of lip and palate. Congenit Anom. 1984;24:75–82. doi: 10.1111/j.1741-4520.1984.tb00009.x. - DOI
    1. Natsume N, Miura S, Kawai T. Effect of sexual differences on the development of cleft palate in the human. Plast Reconstr Surg. 1989;84:854–855. - PubMed
    1. Natsume N, Niimi T, Furukawa H. Survery of congenital anomalies associated with cleft lip and/or palate in 701, 181 Japanese people. Oral Surg Oral Med Oral Pathol Oral Radiol Endod. 2001;191:157–161. doi: 10.1067/moe.2001.112948. - DOI - PubMed
    1. Aragaki K, Sunakawa H, Hiratsuka H. A sixteen-year clinicostatistical analysis of cleft lip and/or palate patients in Department of Oral and Maxillofacial Surgery, School of Medicine, University of the Ryukyus. J Jpn Cleft Palate Assoc. 2003;28:66–73.
    1. Otsuki R, Morita N, Wada T. Clinical and statistical observations of patients with cleft lip and/or palate:-1st report: character of cleft type and complicating malformations. J Jpn Stomatol Soc. 2002;51(2):132–136.

LinkOut - more resources