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Review
. 2012 Feb;12(1):13-7.
doi: 10.1097/ACI.0b013e32834eccdb.

Vitamin D and chronic rhinitis

Waleed M Abuzeid  1 , Nadeem A Akbar, Mark A Zacharek
Affiliations
Review

Vitamin D and chronic rhinitis

Waleed M Abuzeid et al. Curr Opin Allergy Clin Immunol. 2012 Feb.

Abstract

Purpose of review: To discuss the role of vitamin D in chronic rhinitis and chronic rhinosinusitis (CRS).

Recent findings: Vitamin D has been shown to have an immunomodulatory effect with a significant impact on immune function. Specifically, vitamin D regulates the mechanisms which suppress the inflammatory response and direct the differentiation fate of immune cells. Vitamin D has been shown to play an important role in asthma, and the concept of the unified airway model allows the extrapolation of vitamin D as a critical player in chronic rhinitis and rhinosinusitis.

Summary: Recent findings on the function of vitamin D may explain aspects of the pathophysiology of chronic rhinitis and CRS, and may help direct future treatment of these diseases.

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