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. 2011 Dec 1;67(Pt 12):o3441.
doi: 10.1107/S1600536811049324. Epub 2011 Nov 25.

(1R,3S)-N-Benzhydryl-2-benzyl-6,7-dimeth-oxy-1-phenyl-1,2,3,4-tetra-hydro-isoquinoline-3-carbothio-amide

Tricia Naicker, Thavendran Govender, Hendrick G Kruger, Glenn E M Maguire

(1R,3S)-N-Benzhydryl-2-benzyl-6,7-dimeth-oxy-1-phenyl-1,2,3,4-tetra-hydro-isoquinoline-3-carbothio-amide

Tricia Naicker et al. Acta Crystallogr Sect E Struct Rep Online. .

Abstract

The title compound, C(38)H(36)N(2)O(2)S, has a heterocyclic ring that assumes a half-chair conformation. The phenyl rings of neighbouring mol-ecules align forming alternating chains parallel to [100] within the crystal packing. The absolute stereochemistry of the crystal was confirmed to be R,S at the 1- and 3-positions, respectively, by proton NMR spectroscopy. A single intra-molecular N-H⋯N hydrogen bond is observed.

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Figures

Fig. 1.
Fig. 1.
The molecular structure of the title compound with the atom numbering scheme. Displacement ellipsoids are drawn at the 40% probability level. Hydrogen atoms have been omitted for clarity.
Fig. 2.
Fig. 2.
A partial projection of the title compound, viewed along the [100] plane.
See this image and copyright information in PMC

References

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