Shear wave elastography of focal salivary gland lesions: preliminary experience in a routine head and neck US clinic

Abstract

Objectives: To evaluate shear wave elastography (SWE) for focal lesions in major salivary glands.

Methods: Sixty lesions (49 parotid, 11 submandibular) undergoing routine ultrasound (grey scale and Doppler) also underwent SWE before US-guided needle aspiration for cytology. Quantitative indices of the shear elastic modulus (stiffness) were compared with cytological results.

Results: Fifty-five lesions were benign (21 pleomorphic adenomas, 18 Warthin's tumours; 16 others) and 5 malignant (2 mucoepidermoid carcinomas, 1 myoepithelial carcinoma, 1 B-cell lymphoma, 1 nodal metastasis). Shear modulus of benign lesions, median 18.3 kPa, overlapped appreciably with malignant lesions, median 13.5 kPa. However, 2 mucoepidermoid carcinomas had the highest stiffness values (81.9 kPa, 132.0 kPa). Stiffness of pleomorphic adenomas (median 22.5 kPa) was higher than Warthin's tumours (16.9 kPa) (P = 0.05 Mann-Whitney U-test). The standard deviation of stiffness values within a lesion, used as an indicator of spatial heterogeneity, was highest in mucoepidermoid cancers (median 44.2 kPa), followed by pleomorphic adenomas (median 12.4 kPa) and remaining lesions (medians 1.4-10.3 kPa).

Conclusion: This study shows a degree of clustering of SWE indices according to pathology although it appears that SWE has suboptimal performance for ruling out malignancy, thus limiting its use in routine practice.

Key points: • Shear wave elastography is a feasible technique for focal salivary gland lesions. • Elastographic artefacts aggravated by the regional anatomy may hinder this technique. • Elastographic indices vary according to pathology but there is appreciable overlap. • Overlapping indices for malignant and benign lesions limit its utility. • Pleomorphic adenomas have higher elasticity indices, i.e. are stiffer, than Warthin's tumours.