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. 2011:2011:356538.
doi: 10.1155/2011/356538. Epub 2011 Nov 30.

Dilation of malignant strictures in endoscopic ultrasound staging of esophageal cancer and metastatic spread of disease

Shawn M Hancock  1 , Deepak V Gopal, Terrence J Frick, Patrick R Pfau
Affiliations

Dilation of malignant strictures in endoscopic ultrasound staging of esophageal cancer and metastatic spread of disease

Shawn M Hancock et al. Diagn Ther Endosc. 2011.

Abstract

Background. Dilation of malignant strictures in endoscopic ultrasound (EUS) staging of esophageal cancer is safe, but no data exists regarding the subsequent development of metastases. Aim. Compare the rates of metastases in esophageal cancer patients undergoing EUS staging who require esophageal dilation in order to pass the echoendoscope versus those who do not. Methods. We reviewed consecutive patients referred for EUS staging of esophageal cancer. We evaluated whether dilation was necessary in order to pass the echoendoscope, and for the subsequent development of metastases after EUS at various time intervals. Results. Among all patients with similar stage (locally advanced disease, defined as T3, N0, M0 or T1-3, N1, M0), there was no difference between the dilated and nondilated groups in the rates of metastases at 3 months (14% versus 10%), P = 1.0, 6 months (28% versus 20%), P = 0.69, 12 months (43% versus 40%), P = 1.0, or ever during a mean followup of 15 months (71% versus 55%), P = 0.48. Conclusions. Dilation of malignant strictures for EUS staging of esophageal cancer does not appear to lead to higher rates of distant metastases.

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Figures

Figure 1
Figure 1
Development of metastases at any time during a mean followup of 20 months among all patients without metastases present at the time of staging EUS.
Figure 2
Figure 2
Development of metastases at various time intervals after EUS among patients with similar staging-locally advanced disease.
See this image and copyright information in PMC

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