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Comparative Study
. 2012 Apr;132(4):1111-6.
doi: 10.1038/jid.2011.427. Epub 2011 Dec 29.

Physical and mental impact of psoriasis severity as measured by the compact Short Form-12 Health Survey (SF-12) quality of life tool

Ivan Grozdev  1 , Douglas Kast, Lauren Cao, Diana Carlson, Prasad Pujari, Brian Schmotzer, Denise Babineau, Elizabeth Kern, Thomas McCormick, Kevin D Cooper, Neil J Korman
Affiliations
Comparative Study

Physical and mental impact of psoriasis severity as measured by the compact Short Form-12 Health Survey (SF-12) quality of life tool

Ivan Grozdev et al. J Invest Dermatol. 2012 Apr.

Abstract

The Short Form-12 Health Survey (SF-12) is used to assess the patient's quality of life (QoL) using the physical component score (PCS) and the mental component score (MCS). The purpose of this study was to determine whether the SF-12 PCS and MCS are associated with psoriasis severity and to compare QoL between Murdough Family Center for Psoriasis (MFCP) patients and patients with other major chronic diseases included in the National Survey of Functional Health Status data. We used data from 429 adult patients enrolled in MFCP. Psoriasis Area Severity Index (PASI) was used to assess psoriasis severity at the time of completion of the SF-12 questionnaire. Other variables included age, sex, body mass index, psoriatic arthritis, psychiatric disorders, and comorbidities. Linear regression models were used to estimate effect sizes ± 95% confidence intervals. For every 10-point increase in PASI, there was a 1.1 ± 1.3 unit decrease in MCS (P=0.100) and a 2.4 ± 1.3 unit decrease in PCS (P<0.001). Psoriasis severity was associated with PCS and MCS after adjusting for variables, although the strength of the relationship was attenuated in some models. Psoriasis severity is associated with decreased QoL. SF-12 may be a useful tool for assessing QoL among psoriasis patients.

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Conflict of interest statement

CONFLICT OF INTEREST

The authors state no conflict of interest.

Figures

Figure 1
Figure 1. Associations of DLQI with SF-12
Plot of the association between DLQI and MCS (correlation coefficient −0.33). DLQI, Dermatology Life Quality Index; MCS, mental component score; SF-12, the Short Form-12 Health Survey.
Figure 2
Figure 2. Associations of DLQI with SF-12
Plot of the association between DLQI and PCS (correlation coefficient −0.31). DLQI, Dermatology Life Quality Index; PCS, physical component score; SF-12, the Short Form-12 Health Survey.
See this image and copyright information in PMC

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