Influenza A/H1N1 septic shock in a patient with systemic lupus erythematosus. A case report
- PMID: 22206235
- PMCID: PMC3265447
- DOI: 10.1186/1471-2334-11-358
Influenza A/H1N1 septic shock in a patient with systemic lupus erythematosus. A case report
Abstract
Background: Immunocompromised patients, such as systemic lupus erythematosus (SLE) sufferers have an increased risk of mortality, following influenza infection. In the recent pandemic, influenza A H1NI virus caused 18449 deaths, mainly because of adult respiratory distress syndrome or bacterial co-infections.
Case presentation: In this case report, an SLE patient with viral-induced septic shock, without overt pulmonary involvement, is discussed. The patient was administered oseltamivir and supportive treatment, including wide-spectrum antibiotics, vasopressors and steroids, according to the guidelines proposed for bacterial sepsis and septic shock. She finally survived and experienced a lupus flare soon after intensive care unit (ICU) discharge.
Conclusions: To our knowledge, this is the first case to report severe septic shock from influenza A/H1N1 virus, without overt pulmonary involvement.
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References
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- Shieh WJ, Blau DM, Denison AM, Deleon-Carnes M, Adem P, Bhatnagar J, Summer J, Liu L, Patel M, Batten B, Greer P, Jones T, Smith C, Bartlett J, Montague J, White E, Rollin D, Gao R, Seales C, Jost H, Metcalfe M, Goldsmith CS, Humphrey C, Schmitz A, Drew C, Paddock C, Uyeki TM, Zaki SR. 2009 pandemic influenza A H1N1: Pathology and pathogenesis of 100 fatal cases in the United States. Am J Pathol. 2010;177:166–75. doi: 10.2353/ajpath.2010.100115. - DOI - PMC - PubMed
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