[Vitamin D and autoimmunity. First part: Fundamental aspects]
- PMID: 22206605
- DOI: 10.1016/j.revmed.2011.11.009
[Vitamin D and autoimmunity. First part: Fundamental aspects]
Abstract
The effects of vitamin D on calcium homeostasis and bone metabolism are well known. In recent years, suboptimal vitamin D status has been recognized as a pandemic. Meanwhile, extra-skeletal effects of vitamin D are becoming better documented, particularly its effects on immunity. The authors present their actions on myeloid dendritic cells, T cells, B cells, as well as on the synthesis of antimicrobial peptides and autophagy, and the potential beneficial effects in autoimmune and inflammatory diseases.
Copyright © 2011 Société nationale française de médecine interne (SNFMI). Published by Elsevier SAS. All rights reserved.
Comment in
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[Sun and rheumatoid arthritis].Rev Med Interne. 2012 Jun;33(6):351. doi: 10.1016/j.revmed.2012.03.358. Epub 2012 May 8. Rev Med Interne. 2012. PMID: 22572586 French. No abstract available.
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